Copper-catalyzed oxidative CH bond functionalization of N-allylbenzamide for CN and CC bond formation

CH bond functionalization for CN and CC bond formations via cross-dehydrogenative coupling (CDC) of N-allylbenzamides with indole as amine source has been developed under a copper-catalyzed condition. To the best of our knowledge, these are the first examples in which different classes of N-containing compounds were directly prepared from the readily available N-allylbenzamides using an inexpensive catalyst-oxidant (CuSO₄/TBHP) system. Further, it was applied for the synthesis of α-substituted N-allylbenzamides by using Grignard reagent as nucleophiles.     

Stability and Turing Patterns of a Predator-prey Model with Holling Type II Functional Response and Allee Effect in Predator

Acta Mathematicae Applicatae Sinica, English Series - In this paper, we are concerned with a predator-prey model with Holling type II functional response and Allee effect in predator. We first...     

两个基于4-羧酸-2,2':6',2"-三联吡啶的铜配合物的合成、晶体结构及性质

水热法合成了2个配合物{[Cu₂(L)₂(tp)]·2H₂O}_n(1)和[CuL(ClO₄)]_n(2)(L=4-羧酸-2,2':6',2"-三联吡啶,H₂tp=对苯二甲酸)。对其晶体结构进行了分析,结果表明配合物1和2都通过配体和金属离子组装成一维链结构;配合物1属于三斜晶系,P1空间群,并通过链间的氢键作用形成三维的网状结构;配合物2通过链与链间的氢键作用形成二维的层状结构。对其热稳定性和荧光性质进行了研究。     

Application of Langlois' reagent（NaSO2CF3） in C–H functionalisation

The process of selectively introducing a CF₃ group into an organic molecule using inexpensive,stable,and solid sodium trifluoromethanesulfinate has rapidly advanced in recent years to become an eco-friendly method used by organic chemists to synthesize various natural and bioactive molecules.This review focuses on advances made within the last five years regarding C-H functionalisation,namely thermochemical C（sp²）-H（thio）trifluoromethylations,photochemical C（sp²）...     

双一流背景下有机化学精准教学的探究实践*

有机化学课程是本校化学师范和高分子材料与工程2个国家级一流本科专业以及应用化学、制药工程等专业基础必修课程。由于化学师范和非师范专业的培养目标不同,有机化学的精准教学方面也有所差异。主要从理论教学、实验教学和多媒体教学等3个方面对化学师范专业和非师范专业有机化学差异化精准教学进行了探究实践,化学师范专业有机化学的精准教学侧重于培养学生的教学能力,非师范专业有机化学的精准教学侧重于培养学生的应用能力。     

A stable chemiluminophore,adamantylideneadamantane 1,2-dioxetane: from fundamental properties to utilities in mechanochemistry and soft crystal science

Chemiluminescence (CL) is a luminescence phenomenon originated by a “chemical reaction.” CL provides a basis for real-time imaging technology in materials science. In fact, a CL reaction is easily triggered in general and makes it possible to track its progress in a target material by highly sensitive photon detection. Recently, real-time CL imagings became breakthrough techniques for analyzing the molecular mechanisms of failures of polymeric materials and of reactions and phase transitions in soft crystals. In the CL imaging techniques, adamantylideneadamantane 1,2-dioxetane (Adox) has been adopted as a stable core structure of chemiluminophores. That is, Adox is an essential seed compound to design a chemiluminophore with a desired molecular function. To support developments of real-time CL imaging techniques, we review the chemistry of Adox as a representative stable chemiluminophore including scientific history and utilities of Adox and its derivatives.     

Accelerating Electrochemical Reactions in a Voltage-Controlled Interfacial Microreactor

Microdroplet chemistry is attracting increasing attention for accelerated reactions at the solution–air interface. We report herein a voltage-controlled interfacial microreactor that enables acceleration of electrochemical reactions which are not observed in bulk or conventional electrochemical cells. The microreactor is formed at the interface of the Taylor cone in an electrospray emitter with a large orifice, thus allowing continuous contact of the electrode and the reactants at/near the interface. As a proof-of-concept, electrooxidative C−H/N−H coupling and electrooxidation of benzyl alcohol were shown to be accelerated by more than an order of magnitude as compared to the corresponding bulk reactions. The new electrochemical microreactor has unique features that allow i) voltage-controlled acceleration of electrochemical reactions by voltage-dependent formation of the interfacial microreactor; ii) “reversible” electrochemical derivatization; and iii) in situ mechanistic study and capture of key radical intermediates when coupled with mass spectrometry.     

Selection of Planar Chiral Conformations between Pillar[5,6]arenes Induced by Amino Acid Derivatives in Aqueous Media

Chiral α-amino acids play critical roles in the metabolic process in nearly all life forms. So far, chiral recognition of α-amino acids has mainly focused on the determination of l /d enantiomers. Herein, selection of planar chiral conformations between water-soluble pillar[5]arene WP5 and pillar[6]arene WP6 was observed due to α-side chain or ethyl ester moieties of l -α-amino acid ethyl ester hydrochlorides binding with WP5 and WP6 , respectively. Therefore, α-side chain and ethyl ester moieties of l -α-amino acid ethyl ester hydrochlorides were recognized by observing the induced CD signal and its inversion. This is a rare example of being able to detect the chiral region around α-carbon of a chiral α-amino acid molecule.     

复杂网络上的意见动力学对谣言传播的影响

通过在SIR(susceptible-infected-recovered)模型中引入抑制者对谣言的辟谣机制研究了在线社交网络上的意见动力学对谣言传播的影响.在这一模型中,节点可以与自身的邻居组成1个群,传播者可以通过该群传播信息,抑制者也可以在此群中对信息发表意见进行辟谣.辟谣机制在降低未知者对于谣言的接受概率的同时也可以促使传播者向抑制者转变.本文采用ER(Erd?s-Rényi)随机网络、无标度网络以及真实的社交网络研究了抑制者的沉默概率对于谣言传播范围的影响.首先发现,谣言传播的过程以传播者的峰值为界可以分为两个阶段,即谣言自由传播的前期以及抑制者和传播者互相制衡的后期;其次,谣言的传播会随着抑制者的沉默概率的增大而突然暴发.在谣言暴发阈值之下,沉默概率的增大不会导致谣言传播范围显著增大,这是由于未知者在感知到谣言并转变为传播者后又迅速转变为抑制者;而当沉默概率达到谣言暴发阈值时,抑制者将不能控制传播者对谣言的传播从而导致抑制者的降低和谣言的暴发;最后,无标度上的谣言自由传播的前期阶段比随机网络持续的时间更短,从而使无标度上的谣言更难以暴发.本文的模型综合考虑了意见动力学和谣言传播的相互作用,更加真实地模拟了真实世界社交网络中的谣言传播过程.为谣言传播的控制和干预提供了一些有用的思路和见解.     

Double-stranded ladderphanes with C2-symmetric planar chiral ferrocene linkers

Eight ladderphanes with C₂-symmetric planar chiral ferrocene linkers are synthesized by ring opening metathesis polymerization of bisnorbornene monomers using Grubbs-I catalyst. The aminobenzoate in both monomers and polymers shows absorption maximum around 320 nm. Both monomers and polymers are Circular dichroism (CD) active. Little enhancements of CD profiles around 320 nm are observed for ladderphanes having chiral chloro- or phenyl-substituted ferrocene linkers. However, ladderphanes with a phenyl substituent on the cyclopendienyl ring exhibits enhancement of CD curves aound 240–300 nm. The congested phenyl moieties in adjacent linkers in this polymer might be well oriented such that interactions between these aromatic substituents on different monomeric units might provoke the enhancement of the CD curves in this region. When the methyl-substituted cyclopendienyl ligand is used for chiral ferrocene linkers, the ladderphanes exhibit two-fold enhancement of CD spectrum around 320 nm. This enhancement is further increased when the cyclopentadienyl ligand contains an additional phenyl substituent, owing to exciton coupling between aminobenzoate moieties in adjacent monomeric units. Moreover, the intensity of the CD curves in the region of 240–300 nm is significantly increased. These results suggest that the later polymer may adopt a posible helical structure. © 2017 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2017 , 55, 2999–3010